Peptide Complex
GHK-Cu
Buy GHK-Cu in Australia — >99.0% HPLC tested with batch-specific COA. Same-day Australian dispatch.
Copper tripeptide complex research compound. Naturally occurring peptide investigated in gene expression modulation and extracellular matrix regulation.
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GHK-Cu
Estimated launch price: $49 AUD
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Researchers studying GHK-Cu frequently study
GHK-Cu Overview
GHK-Cu is a naturally occurring tripeptide–copper coordination complex composed of glycine, histidine, and lysine bound to a copper(II) ion. First identified in human plasma, the complex has been investigated extensively for its role in modulating gene expression and supporting extracellular matrix dynamics in preclinical research.
History
GHK was originally identified in the early 1970s as a growth factor active in human plasma. The copper-bound complex GHK-Cu was characterised in the 1980s. Modern research has expanded into gene-expression modulation, with reports of effects on hundreds of genes related to repair, regeneration, and cellular homeostasis.
GHK-Cu Structure
Research Findings
GHK-Cu has been studied in skin biology, wound research, and gene-expression profiling. Reports describe modulation of collagen and elastin synthesis, antioxidant gene expression, and ECM remodelling pathways. The copper coordination is functionally essential to activity.
Key Areas of Research:
- •Gene expression: Modulation of repair, regeneration, and antioxidant gene programmes
- •Collagen / ECM: Collagen and elastin synthesis modulation
- •Skin biology: Dermal fibroblast research
- •Wound research: Tissue repair preclinical models
Pickart L. et al. (2015). GHK peptide as a natural modulator of multiple cellular pathways.
References
References are provided for research context. Pillar Research does not endorse or interpret published findings as therapeutic claims.
GHK-Cu — research questions
Common questions for Australian researchers about GHK-Cu.
What is GHK-Cu?
GHK-Cu is a naturally occurring tripeptide–copper(II) coordination complex (Gly-His-Lys-Cu²⁺). It is supplied as an investigational research compound for in vitro laboratory research under the RUO framework.
Why is the copper essential?
The copper coordination is functionally essential to GHK-Cu activity. The apo-tripeptide (without copper) is a chemically and biologically distinct molecule. Research applications targeting the copper-peptide complex must use the GHK-Cu form.
What is GHK-Cu used for in research?
GHK-Cu is investigated in gene-expression modulation and extracellular matrix remodelling research. The copper coordination is functionally essential to the activity studied.
Is GHK-Cu legal in Australia?
GHK-Cu is classified as Schedule 4 (prescription-only) for the copper-peptide complex under the Australian Poisons Standard. It can be lawfully supplied for in vitro research purposes under the Research Use Only (RUO) framework. It is not listed on the Australian Register of Therapeutic Goods (ARTG) and is not a therapeutic good under the Therapeutic Goods Act 1989 (Cth).
How is GHK-Cu verified by Pillar Research?
Every batch is independently HPLC and mass spectrometry verified by a third-party Australian laboratory. The batch-specific Certificate of Analysis is downloadable from this page.
How should GHK-Cu be stored?
Store lyophilised vials at 2–8 °C, protected from light. Avoid acidic solvents during reconstitution that may strip the copper centre. Otherwise standard handling applies.